About the position
The Director, HV&E - Supportive Care will support the strategic goals of the Oncology Division by driving optimal patient access for supportive care medicines. This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal patient access by demonstrating the value of our supportive care medicines. The HV&E Director will be responsible for developing and executing against the global evidence generation strategy, including direct oversight of evidence generation activities and dissemination of technical deliverables. The Director will be part of Pfizer's dynamic Global Access & Value (GAV) team and will have the important role of managing health economics and outcomes research (HEOR) to generate data to support patient access to supportive care medicines, with a focus on ponsegromab. This position will be working closely with the GAV, cross-functional and country teams to foster a culture that promotes innovation and thrives on doing better for Pfizer's patients and healthcare.
Responsibilities
- Provide strategic input into clinical trial designs (eg, patient populations, comparators, endpoints) and analysis to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.
- Develop and execute the clinical outcomes assessment strategy and incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence aligned with overall asset strategy and to ensure global reimbursement and access requirements.
- Lead the development and execution of the Value & Evidence Strategy (VES) to support the value of supportive care assets in the Oncology Division in close partnership with the cross-functional matrix team and local country/regional teams.
- Lead the design and execution of global HEOR studies (eg, network meta-analyses, non-interventional studies, economic models) from concept through publication.
- Lead the timely development of launch deliverables including global value dossiers/AMCP dossiers, systematic literature reviews, economic models, and innovative tools to successfully support reimbursement and access requirements in conjunction with the regions/countries.
- Partner with internal stakeholders to ensure appropriate customer facing dissemination of HEOR materials per regulatory guidance and internal SOPs.
- Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.
Requirements
- Graduate degree required (e.g. MSc, MPH, PhD)
- 7+ years of experience required with MSc/MPH/MBA degree; 5+ years of experience required with PharmD/PhD in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
- Demonstrated in depth understanding of fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation.
- Knowledge and understanding of drug development process
- Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
- Excellent oral and written English communication skills
- Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to business priorities and prioritize accordingly
- An 'execution mindset' focused on getting things done quickly and simply
- Strong project management abilities (contracting, budgeting, vendor management) essential.
- Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
- Ability to influence key members of medical, clinical, and commercial teams constructively and without conflict
- Skilled in functioning within a matrix organization and managing through influence
- Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize and address/resolve issues
- Change oriented and comfortable responding to unexpected demands with tight timelines; team player
Nice-to-haves
- Knowledge and experience in the oncology therapeutic area is highly preferred along with experience with supportive care products
- Experience with creative cost-effective modeling approaches (eg, leveraging aspects of the ISPOR Value Flower)
- Experience interacting with country teams and knowledge of global HTA requirements and HTA organizations (eg, NICE, GBA, HAS, CDA, PBAC, ICER)
Benefits
- 401(k) plan with Pfizer Matching Contributions
- Paid vacation, holiday and personal days
- Paid caregiver/parental and medical leave
- Health benefits to include medical, prescription drug, dental and vision coverage
