A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech, a member of the Roche Group. At Prescient Design, part of Genentech, we are at the forefront of transforming drug discovery through Artificial Intelligence and Machine Learning. We are building the Lab-in-the-Loop, Genentech's cutting-edge AI platform for therapeutic molecular design. This platform is central to accelerating the discovery of new medicines by integrating massive quantities of experimental data to train predictive AI models. We seek an exceptional Principal Software Engineer to take a leading technical role in shaping the design, development, and future direction of this critical platform, enabling AI-driven drug design across Roche. We are seeking a technical leader with deep full-stack expertise, particularly skilled in building intuitive front-end experiences and scalable backend systems. The ideal candidate possesses strong product intuition, a keen eye for user experience, and proven experience in shaping technical roadmaps and designing robust service architectures for complex platforms. You thrive on technical ownership and guiding the evolution of a product from concept to production, influencing its capabilities and impact.