Analytical Development Principal Research Scientist

Vertex Pharmaceuticals • Boston, MA

4d • Onsite

About The Position

General Summary: Vertex is seeking a talented scientist to join our small molecules Analytical Development group in Boston, MA. This individual will play a central role in advancing transformative medicines by leading analytical chemistry activities for small molecule development programs from preclinical through to Phase 1. This role includes representing Analytical Development at cross-functional project team meetings and so demonstrable experience to resolve project challenges in collaboration with other R&D functions is required. The ability to work both independently and in a matrix team environment is essential to succeed in this position. Key Duties and Responsibilities: Project oversight: represent Analytical Development at cross-functional teams and effectively communicates issues and solutions to colleagues at all levels within the organization. Strategy: develop, align and execute analytical project team plans and strategies to support drug substance and drug product development including method development, stability and validation activities. Laboratory expertise: apply advanced analytical skills and understanding in laboratory techniques routinely used in the analysis of drug substance and drug product samples. Collaboration: work both independently and collaboratively within a matrix team environment. Communication: demonstrated ability to effectively present results in both oral and written reports and to productively disseminate ideas across discipline and project boundaries. Advance strategic initiatives: develop, contribute and support new ways of working, operating models and paradigms that improve productivity, efficiency and overall effectiveness of workflows and processes

Requirements

• Experienced Analytical Lead ( preclinical to Phase 1) in the pharmaceutical or biotechnology industry
• The ability to work successfully in both a team/matrix environment as well as independently
• Technical expertise in analytical techniques that include LC, GC, KF, NMR, XRF etc
• Advanced troubleshooting skills and problem-solving capabilities
• Strong analytical data assessment, review and interpretation skills
• Advanced experience in communication of technical data: writing reports and presentation skills
• High attention to detail
• Ability to work in a fast-paced environment, managing priorities and maintaining timelines
• Strong knowledge of cGMPs and pharmaceutically relevant regulatory guidelines
• Ph.D. with 4-7 years, Master’s degree with 7+ years, or Bachelor’s degree with 10+ years of relevant professional analytical development experience in the pharmaceutical industry

Responsibilities

• Project oversight: represent Analytical Development at cross-functional teams and effectively communicates issues and solutions to colleagues at all levels within the organization.
• Strategy: develop, align and execute analytical project team plans and strategies to support drug substance and drug product development including method development, stability and validation activities.
• Laboratory expertise: apply advanced analytical skills and understanding in laboratory techniques routinely used in the analysis of drug substance and drug product samples.
• Collaboration: work both independently and collaboratively within a matrix team environment.
• Communication: demonstrated ability to effectively present results in both oral and written reports and to productively disseminate ideas across discipline and project boundaries.
• Advance strategic initiatives: develop, contribute and support new ways of working, operating models and paradigms that improve productivity, efficiency and overall effectiveness of workflows and processes

Benefits

• This role is eligible for an annual bonus and annual equity awards.
• Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
• At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
• From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree