Associate Scientist I, mRNA Process Development

Strand Therapeutics•Boston, MA

10h•$74,000 - $79,000

About The Position

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Associate Scientist I of mRNA Process Development. The expectation is that the Associate Scientist I will have experience independently executing mRNA process development experiments and production efforts. Reporting to Principal Associate Scientist of mRNA Process Development, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a desire to conquer new challenges.

Requirements

BS with 1-2+ years of directly related experience. Degree emphasis in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field preferred.
This position requires conducting laboratory experiments, excellent documentation review and writing skills, and the flexibility to work on multiple projects as needed.
Basic knowledge of purification of biologics such as chromatography and filtration.
Understanding of nucleic acid chemistry, enzymatic and chemical reactions, PCR, plasmid processing, and standard analytical techniques for macromolecules.
Availability to be able to work flexible hours/shifts required.
Track record of completing deliverables within specified timelines.
Independently motivated, thinks outside the box, and good problem-solving ability.
Excellent organizational skills and attention to detail.
Able to multi-task in an extremely fast-paced environment with changing priorities.

Nice To Haves

Knowledge of ÄKTA systems and UNICORN control software preferred.
Experience with TFF and UFDF principles preferred.

Responsibilities

Responsible for execution of mRNA production and purification development activities appropriate for GMP manufacturing.
Responsible for running and developing analytical methods and assays.
Support screening, optimization, and scale-up efforts for enzymatic reactions, chromatographic separations and filtration processes including, ultrafiltration, diafiltration, and sterile filtration.
Assist with production of materials for formulation and discovery experiments
Execute studies for process improvements and advancements.