Clinical Operations Director (Oncology) Asset Lead

GSK•Upper Providence, PA

2d•Hybrid

About The Position

Job Purpose: You will lead and develop the program level operational strategy and delivery plan for an asset, ensuring studies run safely and efficiently. You will work with cross-functional partners to keep programs inspection ready and to deliver high-quality data for regulatory interactions. We value clear judgement, practical problem solving, and collaborative leadership. This role offers strong learning and career growth, and the chance to make meaningful impact aligned with GSK’s mission of uniting science, technology and talent to get ahead of disease together.

Requirements

Advanced degree in MD, PharmD, PhD or related field, or equivalent clinical experience.
8+ years of clinical development experience, with oncology exposure.
3+ years of experience leading R&D interventional studies (Phase I, II, III).
Experience in managing cross-functional, matrixed teams with defined deliverables and performance outcomes.
Experience in clinical trial design, safety governance and regulatory submission requirements.
Experience in managing clinical research projects or equivalent in at least 2 different TA
Experience in project development, quality requirements and associated processes.
Experience in clinical development and matrix management.
Create and implement multi-year, cross‑functional operational plans across multiple streams and indications for single asset or multiple interdependent assets.
Experience converting scientific, strategic, and stakeholder input into documented action plans, timelines, and execution frameworks for the Asset team.
Experience applying defined prioritization criteria (risk, impact, resources, dependencies) to rank activities and coordinate stakeholder needs while aligning therapeutic area (TA) objectives with asset‑specific goals.
Experience in coordinating communication, decision inputs, and deliverables with senior leadership, including SVP and C‑suite stakeholders.
Experience developing and presenting structured reports, analyses, and recommendations that distill complex scientific and operational data into clear decision-ready formats for senior leadership.

Responsibilities

Lead asset-level clinical operations planning to maintain inspection readiness and regulatory deliverables.
Contribute to the development of the Clinical Development Plan and Integrated Evidence Plan
Represent Global Clinical Operations functions at the asset level.
Coordinate cross-functional partners (clinical, biostatistics, clinical supplies, safety, and vendors) to support timely data deliveries.
Oversee vendor selection, contracting input, and operational oversight for outsourced clinical activities.
Model scenarios for optimal asset/study delivery linked to value drivers and drives decisions presented to governance boards
Maintain and drive implementation of asset-level operational risk and mitigation plans.
Drive innovative approaches to study execution through external facing advances in technology and sciences, by identifying and embracing risks and opportunity
Provide strategic guidance and leadership to Study Delivery Teams to ensure clinical project goals are met.
Prepare and respond to data requests and contribute to materials for regulatory submissions.