Clinical Trial Manager

Ossium Health•San Francisco, CA

9h•$145,000 - $165,000•Hybrid

About The Position

We are hiring a Clinical Trial Manager to support the successful execution of our clinical trials and operations. In this role, you’ll take ownership of the day-to-day tactical management of ongoing studies, ensuring seamless trial implementation and monitoring. You’ll play a key role in launching our PRESERVE II clinical trial, the long-term follow-up of PRESERVE I, and our HOPE expanded access program. This position is ideal for someone who thrives in a hands-on, fast-paced environment—someone eager to collaborate across teams and coordinate with internal partners, CROs, and external vendors to deliver excellence in every aspect of our trials. This role reports to the Senior Director, Clinical Operations.

Requirements

Degree in Life Sciences & industry-sponsored clinical trial experience: BS & 3+ years MS/MPH & 1+ years
Experience with or managing CROs; either from within a CRO in a major role, or from a sponsor-side biotech or pharmaceutical company at the Clinical Trial Manager or Clinical Project Manager level
Strong written and verbal communication skills, with the ability to share complex information clearly and effectively across teams and stakeholders
Exceptional organizational and time management abilities, with comfort operating in a fast-moving, dynamic startup environment
Proven capacity to manage multiple priorities simultaneously, maintaining accuracy and attention to detail
A collaborative, execution-oriented mindset with the ability to build alignment and drive progress across cross-functional teams
This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
Ability to travel as needed (10% - 15%)
Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Nice To Haves

CRA/site coordinator experience
Trial experiences in full life cycle of clinical trial
Experience in cell therapy
Experience in rare disease; hematologic malignancies (specifically bone marrow transplant)

Responsibilities

Serve as the primary liaison with the CRO supporting PRESERVE II study activities, ensuring alignment on timelines and deliverables
Review and contribute clinical operations input to key study documents including protocols, investigator brochures, regulatory submissions, clinical study reports, and operational plans developed by CRO partners
Oversee site feasibility and capability assessments in close collaboration with the CRO and cross-functional teams
Support additional clinical programs and studies as assigned, working closely with the Senior Director, Clinical Operations to meet strategic and operational objectives
Partner with cross-functional groups, including Transplant Operations, Regulatory Affairs, and other stakeholders to ensure seamless coordination and successful trial execution
Help lead and monitor trial execution to ensure compliance with ICH/GCP guidelines, applicable regulations, and company policies
Organize and lead internal clinical project meetings, fostering collaboration and keeping teams aligned on goals and progress