Director, Data Management
About The Position
Join us at Maze Therapeutics as our Director of Data Management, where you will play a key role in shaping the data strategy that supports our clinical development programs. You’ll partner closely with Biostatistics, Statistical Programming, Clinical Operations, and Regulatory Affairs, and oversee external vendors to deliver high-quality, reliable clinical data across our studies. Reporting to the Vice President of Biometrics, you’ll provide strategic direction and hands-on leadership for clinical data management activities spanning multiple clinical trials. Your work will ensure timely, compliant, and analysis-ready data that supports regulatory submissions and key program decisions.
Requirements
- Bachelor’s or advanced degree in Life Sciences, Computer Science, or related field
- 8+ years of clinical data management experience in biotech, pharmaceutical, or CRO environments
- 3+ years of people and/or project leadership experience
- Hands-on experience with EDC systems (e.g., Medidata Rave, Oracle InForm)
- Strong understanding of clinical trial operations, data flows, and regulatory expectations
- Collaborative, mentorship-oriented leadership stylewith the ability to influence across teams
Responsibilities
- Lead data management activities across multiple clinical studies and development phases.
- Shape and implement data management strategies, standards, and best practices.
- Mentor and support data management team members, fostering growth and knowledge sharing.
- Serve as a subject matter expert for data management processes, systems, and regulatory expectations.
- Oversee critical study deliverables including DMPs, CRFs/eCRFs, edit checks, and database locks.
- Guide accurate, consistent, and timely clinical data collection, cleaning, and reconciliation.
- Review and approve key study documentation and ensure readiness for analysis and reporting.
- Drive database lock planning and partner closely with Biostatistics and Medical Writing to support analyses and study reports.
- Manage CROs and external vendors, ensuring clarity around timelines, quality expectations, and contractual commitments.
- Support the evaluation, implementation, and optimization of EDC and data management technologies.
- Collaborate closely with Clinical Operations, Biostatistics, and other partners across the organization.
- Provide data management insights for protocols, study design, and operational planning, while proactively communicating risks and mitigation strategies to senior leadership.
Benefits
- competitive medical, dental, and vision insurance
- mental health offerings
- equity incentive plan
- 401(k) program with employer match
- generous holiday and PTO policy
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Director
