Director, HR Business Partner (Boston)

Vertex Pharmaceuticals • Boston, MA

1d • Hybrid

About The Position

We are seeking a strategic, influential, and agile HR Business Partner Director to lead talent strategies for key Global Medicines Development (GMDA) functions at Vertex . This Director will play a critical role in achieving the GMDA vision of enhancing leadership, driving innovation, enabling top-tier execution, and integrating technology to achieve superior performance across a diverse development pipeline. This role will serve as a trusted advisor to GMDA leaders and their leadership teams, shaping organizational design, culture, and workforce strategies that enable clinical development innovation, execution and long term pipeline success . Reporting to the Lead HRBP for the Chief Medical Officer and the Global Medicines Development organization , this individual will sit on GMDA functional leadershi p teams and play a critical role in driving enterprise-wide HR initiatives and change leadership, enabling organizational effectiveness across clinical development functions. Thi s role shapes and executes talent strategies that strengthen leadership, enable scientific excellence, and support Vertex’s mission to bring transformative therapies to patients.

Requirements

• 10+ years progressive HR experience, including HRBP support for scientific, clinical, or highly regulated functions OR experience in an HR Center of Excellence ( e.g. Organizational Design, Talent Development, etc.)
• Deep experience advising senior leaders and leading enterprise talent processes.
• Strong organizational design capability and experience navigating matrixed R&D organizations.
• Ability to interpret complex business, scientific, and portfolio data to inform organizational decisions.
• Demonstrated expertise in change leadership and coaching.
• Excellent judgment, discretion, and relationship management skills.

Nice To Haves

• Experience supporting global clinical development, PV/safety, biometrics, or GxP impacted teams.
• Experience leading or supporting workforce transformation initiatives involving automation, digital enablement, or AI augmented work , ideally within clinical development, medical affairs, biometrics, or other scientific/regulated environments.
• Background partnering with Digital/Tech, Data Science, or Analytics teams to understand technological impacts on roles, skills, org design, and future capability needs.
• Master’s degree in HR, Business, Organizational Psychology, or related field.
• Experience in high-growth biotechnology or pharmaceutical environments.

Responsibilities

• Strategic & Organizational Leadership Serve as a thought partner to GMDA senior l eadership; contribute to functional strategy with talent, organizational, and culture insights.
• Anticipate organizational needs across development functions , recommending structure, capabilities, and workforce strategies to enable program success.
• Lead organizational design efforts to support portfolio growth, regulatory milestones, country expansion, and long - range planning.
• Use data and insights to influence decision - making around resourcing, span of control, efficiency, and succession.
• Workforce Transformation, Automation & AI Enablement Partner with GMDA leadership to rethink workforce design in light of emerging AI, automation, and technology , capabilities.
• Assess roles, skills, processes, and organizational structures to identify opportunities for AI enabled efficiency, including workflow automation, data driven decision support, and elimination or redesign of low value manual work.
• Collaborate with cross functional teams (e.g., DTE , Talent COE) to ensure GMDA organizations are future-ready with the right capabilities, spans/layers, and operating models.
• Lead workforce planning efforts that incorporate AI- augmented job design, talent upskilling, and reskilling pathways to ensure teams can fully leverage new technologies .
• Guide leaders through change adoption, ensuring employees have the mindset, tools, and capabilities needed to operate effectively in an increasingly automated and analytical environment.
• Anticipate workforce impacts of new technology and partner closely with PX Advisors and relevant COEs when role changes may result from automation, applying all appropriate guidelines and internal processes.
• Enterprise Talent Leadership Lead annual talent cycles for GMDA functions : succession, performance, promotions, compensation, and leadership pipelines.
• Ensure fair, consistent, behavior and results- based assessment practices, and partner with COEs to mitigate bias.
• Coach leaders on talent investments, mobility, pipelines, and organizational bench strength.
• Leader Coaching & Advisory Serve as a trusted coach to senior GMDA leaders , enabling stronger people leadership, effective decision making, and high p erformance teams
• Workforce Planning & Organizational Health Lead multi year capability planning tied to pipeline, regulatory filings, and l ifecycle management
• Analyze organizational health indicators, engagement data, talent flows, and workday talent insights to drive targeted action plans.
• Shape GMDA workforce strategy to ensure alignment with global footprint, functional maturity, and scientific needs.
• Compensation & Job Architecture Partnership Advise leaders on job leveling, architecture, and compensation frameworks; partner with Compensation COE for annual processes.
• Support consistent application of guidelines across GMDA teams, including global teams with diverse market norms.

Benefits

• This role is eligible for an annual bonus and annual equity awards.
• Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
• At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
• From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

What This Job Offers

• Job Type: Full-time
• Career Level: Director