Engineer – Drug Product, Synthetic Molecule Design and Development (SMDD)
About The Position
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. Position Summary: Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization of drug substances and drug products. Our scientists and engineers develop key technical and business solutions across the portfolio using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. SMDD delivers on these responsibilities by recognizing diverse talent and cultures are necessary to bring the next generation of life changing medicines to patients. SMDD is seeking outstanding engineering candidates to work within the process design and development team. The position presents an opportunity to work side by side with chemists, analytical chemists, engineers, formulation scientists and modelers to develop new technical solutions to accelerate our portfolio. The position will be based in Indianapolis where research is conducted in our development facilities.
Requirements
- B.S (0-12 years industry experience). or M.S. (0-9 years industry experience) in chemical engineering or closely related field.
Nice To Haves
- Strong technical skills in drug product development with experience as a hands-on technical contributor in a laboratory/pilot plant environment within pharmaceuticals is desired.
- Demonstrated problem solving skills, attention to detail and result-orientated behaviors in a fast-paced environment.
- Strong verbal and written communication skills and ability to collaborate in a team environment.
- Ability to prioritize multiple activities and handle ambiguity.
Responsibilities
- Apply engineering fundamentals towards designing and optimizing continuous and batch drug product processes at lab, pilot, and manufacturing scales, including but not limited to powder feeding, powder mixing, wet and dry granulation techniques, encapsulation, tablet compaction, spray dry dispersion, hot melt extrusion, and tablet film coating, to ensure successful scale-up of processes through fundamental engineering principles and equipment knowledge.
- Design and execute experiments in a laboratory/pilot plant setting and/or leverage scale-up and process control models to ensure robust processes capable of meeting early and late phase demands by planning and managing both short-term and long-term development activities.
- Develop and review work plans and timelines for project work, recommending resource allocation to accomplish the projects, provide updates, and communicate progress/needs.
- Help to develop stage-appropriate process control strategies encompassing necessary aspects such as equipment operations, automation systems, PAT, model-based predictions, and methods of data reconciliation and monitoring in real time.
- Engineers in SMDD will be responsible for overseeing scaleup and technology transfer to manufacturing facilities within and external to Lilly through team meetings, site visits, and process monitoring.
- Author and maintain documentation such as laboratory notebooks, technical reports, and regulatory submissions dealing with the work performed by the department, including preparation or oversight and review of the appropriate manufacturing and controls portion of regulatory submissions.
- Stay informed about new technology and best practices. Propose, justify, evaluate, and implement new equipment, processing techniques, and technologies.
- Utilize technology to improve safety, quality, and productivity, both in development and manufacturing.
- Foster an inclusive environment by promoting diverse thought and shared experience to deliver innovative solutions that address unmet technical needs.
- Publish and share original research externally through peer-reviewed articles and conferences.
Benefits
- Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Number of Employees
5,001-10,000 employees
