Lab Specialist - Tsai Lab
About The Position
The Department of Molecular Physiology and Biological Physics seeks a Lab Specialist for the Tsai Lab. Lab specialist is responsible for investigating how mitochondrial calcium transport proteins regulate cardiac physiology and contribute to heart diseases using mouse models and induced pluripotency stem cells (iPS). He/she will use CRISPR/Cas9 to knock out various mitochondrial proteins in mice and assess the impact on heart functions, and will also use iPS derived from patients to interrogate the relationship between abnormal mitochondrial calcium and heart diseases. Lab Specialist employees provide technical lab support by performing complex lab and research related tasks. They act as specialists on research methods and equipment functions specific to investigations. They have the authority to adapt methods and procedures to meet the needs of research. They are distinguished from Lab Technicians by the types and duration of assignments, as well as the skills and expertise necessary to serve as resources on non-routine problems. Lab Specialist employees perform daily activities without supervision; their longer-term assignments require greater oversight. Lab Specialist employees often train others on work processes and policies. Specialize in lab and/or other research methods and equipment functions specific to Principal Investigators and/or labs. Demonstrate expertise in troubleshooting problems and recommending solutions. Perform a variety of tests requiring high degree of proficiency. Assist in evaluation of research methods, procedures, and techniques based on established objectives. May perform small animal surgery. Provide basic assistance to researchers in manipulating, computing, and analyzing data using specialized statistical computer software. Evaluate experiment results using statistical and multivariate analyses. Research, compile, and maintain complex statistical, numerical, and computerized reports. Perform library and literature research. Assist in instructing lab academic sections in lab methods, procedures, and safety. Explain work instructions and may adapt general methods and procedures in order to meet the needs of the research. Assist in training other staff members on procedures. In addition to the above job responsibilities, other duties may be assigned
Requirements
- Bachelor's degree
- 1+ year of relevant lab experience required
Responsibilities
- Investigating how mitochondrial calcium transport proteins regulate cardiac physiology and contribute to heart diseases using mouse models and induced pluripotency stem cells (iPS)
- Use CRISPR/Cas9 to knock out various mitochondrial proteins in mice and assess the impact on heart functions
- Use iPS derived from patients to interrogate the relationship between abnormal mitochondrial calcium and heart diseases
- Provide technical lab support by performing complex lab and research related tasks
- Act as specialists on research methods and equipment functions specific to investigations
- Adapt methods and procedures to meet the needs of research
- Serve as resources on non-routine problems
- Train others on work processes and policies
- Specialize in lab and/or other research methods and equipment functions specific to Principal Investigators and/or labs
- Demonstrate expertise in troubleshooting problems and recommending solutions
- Perform a variety of tests requiring high degree of proficiency
- Assist in evaluation of research methods, procedures, and techniques based on established objectives
- May perform small animal surgery
- Provide basic assistance to researchers in manipulating, computing, and analyzing data using specialized statistical computer software
- Evaluate experiment results using statistical and multivariate analyses
- Research, compile, and maintain complex statistical, numerical, and computerized reports
- Perform library and literature research
- Assist in instructing lab academic sections in lab methods, procedures, and safety
- Explain work instructions and may adapt general methods and procedures in order to meet the needs of the research
- Assist in training other staff members on procedures
- Other duties may be assigned
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
