Molecular Pharmacology Scientist

Givaudan SA•Cincinnati, OH

2d•$96,000 - $130,000•Onsite

About The Position

Givaudan's Flavors Science & Technology department is looking for a Molecular Pharmacologist to join our versatile team and promote the latest flavor ingredient discovery. You will use your knowledge in molecular biology, receptor pharmacology, and advanced biological assay techniques to support flavor ingredient discovery from screening through lead optimization. Working with cheminformatics, chemistry, natural products, and sensory teams, you will help solve important challenges in taste modulation through rigorous, data-driven science.

Requirements

PhD in Molecular Pharmacology
2–3 years of experience in pharmaceutical or biotechnology industries; alternatively, 2–3 years of postdoctoral research focused on GPCRs
In-depth knowledge of receptor pharmacology with practical experience working with GPCRs
3+ years of experience with cell-based techniques including Fluorescence Imaging, HTRF, NanoBRET, Tag-Lite, and AlphaScreen
Expertise in the development of in vitro biological assays supporting small-molecule discovery programs
Demonstrated scientific rigor in critically reviewing data and independently formulating and testing novel scientific hypotheses
Demonstrate a scientific approach grounded in creativity and data-driven decision-making.
Communicate complex scientific concepts to team members.

Nice To Haves

Experience using AlphaFold and Cryo-EM 3D structural models to interrogate GPCR pharmacology is highly desirable
Experience managing external studies at CROs or universities (desirable)

Responsibilities

Provide insight and lead in vitro biology assay development to support flavor ingredient discovery programs, from screening to lead optimization
Guide in vitro biology strategies for exploratory and early-stage discovery efforts
Manage experimental design, development, and implementation of cell-based assays for small molecule discovery projects
Apply advanced biological assay techniques to discover and develop novel flavor ingredients
Oversee review, analysis, and interpretation of in vitro data
Translate experimental results to improve understanding of taste and olfaction and elucidate how receptor-active substances modulate sensory endpoints.
Collaborate with researchers in cheminformatics, chemistry, natural products, and sensory teams
Collaborate with functional experts to identify novel research approaches supporting long-term strategic targets
Build and facilitate collaborations with academic partners, CROs, universities, and the broader Givaudan scientific network
Mentor junior scientists in developing skills essential for rigorous research execution
Present research findings through peer-reviewed publications, scientific meetings (talks and posters), and internal presentations
Represent research programs to Givaudan leadership
Ensure all research and discovery activities meet the highest quality, ethical, regulatory, QC, and compliance standards