MSAT Emerging Technical Post Doc

Johnson & JohnsonSpring House, PA
9dOnsite

About The Position

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Johnson & Johnson Innovative Medicine is currently seeking a Post-doctoral Scientist –based in Spring House, PA. About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine The Manufacturing Science and Technology (MSAT) group is looking for a post-doctoral scientist to join the Emerging Technologies team to implement innovative solutions to improve manufacturing. Our team innovates processes to improve reliability and yield and implements process analytical technology (PAT) sensors and machine learning modeling to support next-generation manufacturing of biopharmaceuticals. Support for biopharmaceuticals require fresh thinking to support real time measurements for product quality attributes through the use of PAT. PAT is a key enabler of process intensification, advanced process control (APC) and real time release testing (RTRt) initiatives for pharmaceutical manufacturing. The candidate will design research around novel PAT and data analytics technology on a development scale to support commercial scale implementation. Although we support all therapeutic platforms, a focus in our large molecule drug substance and drug product are prioritized critical initiatives. The candidate will be responsible for design and execution of lab-scale protocols to develop the technology and develop business cases to support commercial implementation. The candidate will develop multivariate models to improve the production of selected proteins and support real time release initiatives.

Requirements

  • Ph.D. with 0-2 years experience in Chemistry, Chemical Engineering, Bioengineering, or related field.
  • Exhibit strong understanding of material characterization methods, including spectroscopy, microscopy, thermal, and physical methods.
  • Training in analytics and statistics to analyze information and draw conclusions based upon their findings.
  • Exhibit strong understanding of biotherapeutic manufacturing operations such as cell culture, protein purification, or formulation.
  • Excellent communication, verbal, written, and presentation skills.

Nice To Haves

  • Proficient in programming languages such as R, Matlab, Python.

Responsibilities

  • Evaluate new PAT sensors
  • Lead activities associated with ongoing multivariate analysis projects
  • Invent, lead and complete projects using mechanistic modeling and/or PAT projects for implementation in manufacturing
  • Collaborate with various other functions within the larger MSAT and R&D teams
  • Develop, validate, and implement high impact innovative solutions in a GMP environment
  • Develop new strategies for product intensification, real time release and advanced process control for next generation manufacturing
  • Authoring technical reports and manuscripts for peer-reviewed publications
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