Nurse Practitioner / Physician Assistant - Gene Therapy

Children’s Hospital of Philadelphia•Philadelphia, PA

About The Position

The Clinical In Vivo Gene Therapy (CIGT) Nurse Practitioner (NP) or Physician Assistant (PA) is responsible for the direct patient care of gene therapy recipients as well as systems development for these patients. They will be involved in the follow-up of a population of patients that matches his/her delineation of privileges and skill set. The components of the role include clinical practice, consultation, quality improvement, professional development, education, and research. The CIGT APP will partner with the CIGT medical director to support the care of clinical and research patients receiving in vivo gene therapies. This position will have an integral role on the gene team consult service, working within a multi-disciplinary team and reporting to the CIGT medical director to coordinate and deliver high-quality care to those who experience gene therapy complications. Additionally, the CIGT APP will work with CIGT research leadership to help provide clinical support of industry and investigator initiated clinical trials, particularly around high-risk toxicity windows coordinating laboratory follow up. The CIGT APP will be responsible for developing and maintaining relationships with internal and, as necessary, external providers to ensure clinical and operational effectiveness and may provide support of institutional initiatives with a focus on safety, quality, operational excellence, financial stewardship, patient-family experience, cultural awareness, and promotion of interdisciplinary collaboration as it relates to gene therapy recipients. This role will liaise closely with the CIGT medical director to support initiatives around best practices, QI, operational efficiency, long-term follow up of gene therapy recipients, and physician and staff training.

Requirements

Master's Degree Nursing Required
Master's Degree - Physician Assistant Required
Ability to work in an inter-professional team setting with multiple responsibilities.
Ability to use computer and electronic medical records effectively.
Refer to Scope of Practice Document and Clinical Responsibilities Checklist for specific requirements of role.
Basic use of a computer (mouse, keyboard, printer, USB ports).
Basic use of Microsoft Office (Word processing, spreadsheets, presentations and Skype).
Web browsing, intranet search, document access.
Use of shared network file space.
Basic use of patient facing technology. (e.g. IV pumps, point of care devices, CR monitors).
Navigation and use of clinical communication systems.
Determines the nature and extent of clinical information needed and uses the appropriate technology to access it.
Accesses needed information effectively and efficiently.
Evaluates information and its sources critically and appropriately incorporates it into clinical practice.
Evaluates outcomes of the use of information.
Navigation of the electronic health record system.
Ability to locate and review specific patient data in various clinical information systems.
Effectively uses clinical decision support tools.
Understands policies and procedures, confidentiality, security, and privacy regulations regarding the use of clinical information systems.
Ability to collect clinical data using quality improvement tools.
Registered Nurse (Pennsylvania) - Pennsylvania State Licensing Board - upon hire - Required or
Registered Nurse (New Jersey) - New Jersey State Licensing Board - upon hire - Required and
Certified Registered Nurse Practitioner (CRNP) (Pennsylvania) - Pennsylvania State Licensing Board - upon hire - Required or
Advanced Practice Nurse (APN) (New Jersey) - New Jersey State Licensing Board - upon hire - Required and
Prescriptive Authority (Pennsylvania) - Pennsylvania State Licensing Board - within 3 months - Required or
Prescriptive Authority (New Jersey) - New Jersey State Licensing Board - within 3 months - Required and
Specialty Certification - in area of education/subspecialty. Required certification must match scope of practice for that practice area. - upon hire - Required
Required (upon hire in Pennsylvania): Certified Physician Assistant (PA-C) (Pennsylvania) - Pennsylvania State Licensing Board
Required (upon hire in New Jersey): Certified Physician Assistant (PA-C) (New Jersey) - New Jersey State Licensing Board
Required (upon hire): Certified Physician Assistant (PA-C) - National Commission on Certification of Physician Assistants

Responsibilities

Develops and co-develops appropriate policies, pathways, and workflows for gene therapy patients supporting safe, high-value, and high-quality care. Collaborates to co-design and implement change in close collaboration with CIGT medical director.
Inpatient rounding and care coordination with as a key member of the multidisciplinary gene therapy consult team (the “gene team”).
In this capacity, rounds on all patients with planned admissions for in vivo gene therapy as well as on patients who are admitted with complications daily (weekdays) as clinically indicated.
Collaborates with attending physicians and other clinical leaders/providers to ensure highly effective and efficient care for gene therapy patients and that the plan of care is properly documented.
Utilizes advanced assessment skills to manage a cohort of patients. Performs and documents daily assessments. Collects and analyzes data and formulates a family-centered plan of care
Evaluates and monitors the effectiveness of the prescribed Gene team treatment plan. Using the most current evidence, modifies the plan of care based on the effectiveness of the treatment and the patient/family response to the plan.
Maintains a list of active gene therapy patients (both clinical and research) with their associated labs and clinical courses
Organizes and leads a weekly gene therapy rounds meeting, where all active and upcoming patients are reviewed and presented
Assists with patient follow up with the primary teams following the weekly meeting
Participates in the care of research and commercial gene therapy patients, serving as a partner for clinical divisions administering gene therapy
Serves as a liaison between CIGT and clinical divisions implementing new gene therapy products. May embed within clinics for 2-3 months at a time in divisions launching clinical gene therapy products. Supports APPs and nursing staff in other divisions during clinical launches. Serves as a resource for other teams as needed.
Ensures clinical and research patients are appropriately added to the CIGT Healthy Planet database. Regularly reviews Healthy Planet database and tracks appropriate metrics.
Serves as an educational resource to the patient/family, nursing staff, and provider team. Acts as a consultant to multidisciplinary health care team members
Oversees and/or performs all aspects of clinical research, and serves as a key member of the CIGT research team
Understand good clinical practice (GCP) and regulatory compliance
Documents investigational product (drug/device) accountability.
Complies with institutional, federal, state, and sponsor policies, standard operating procedures (SOPs) and guidelines.
Serves in a leadership/supervisory capacity on clinical research team. Participates in hiring, supervision, and training of new staff as designated by CIGT leadership Acts as mentor to others for their professional development.
Participates in clinical research committees/activities. Represents CHOP on multicenter clinical research committees.
Demonstrates independent decision making, patient care, and organizational skills beyond that of Clinical Research Nurse.
Performs any needed advanced procedures that are approved as a part of the credentialing process, as required by individual study protocols.
Participates as needed/required by individual study protocols in the outpatient and inpatient evaluation of children who were enrolled in clinical research protocols.
Oversees gene therapy education of other CIGT team members (clinical research associates).
Coordinates regular educational conferences to enhance professional development. Serves as an educational resource for research teams outside of CIGT.