Postdoctoral Fellow-MSH-12906-058

Mount Sinai Health SystemNew York, NY
4d

About The Position

A postdoctoral associate position is available to study HIV-associated neuroinflammation and CNS HIV persistence using advanced humanized mouse models. This position is supported by a newly funded NIH award focused on targeting the NLRP3 inflammasome as a driver of neuroinflammation, blood–brain barrier dysfunction, and latent HIV reservoirs in the central nervous system. The postdoctoral fellow will lead projects using state-of-the-art humanized mouse models of CNS HIV infection to define how innate immune signaling and inflammasome activation in microglia regulate neuroinflammation, BBB integrity, and HIV latency under antiretroviral therapy.

Requirements

  • Expertise in one or more of the following: HIV virology and latency, Humanized mouse models, In vivo immunology, Neuroimmunology or CNS infection, Viral pathogenesis and tissue reservoirs
  • A PhD and/or MD and a strong publication record are required.

Responsibilities

  • Humanized mouse models of CNS HIV infection
  • In vivo immunology and neuroimmune interactions
  • HIV virology and latency in tissue reservoirs
  • Inflammasome biology and innate immune signaling
  • Viral and host immune phenotyping in brain and peripheral tissues
  • Translational testing of immunomodulatory and antiviral strategies
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