Principal Research Associate, Antibody & Protein Engineering

Adimab•Lebanon, NH

About The Position

Adimab is the leading technology provider for therapeutic antibody drug discovery, focusing solely on our partnerships without pursuing an internal product pipeline. Since 2009, we have partnered with over 140 pharmaceutical and biotechnology companies, generating more than 650 therapeutic programs, of which more than 85 have entered clinical trials. Role Overview: We are seeking an experienced, self-motivated, and enthusiastic protein engineer to join our Platform Technologies team. The Principal Research Associate will work in a small, collaborative team to execute and advance Adimab’s platform for the discovery and optimization of protein-based therapeutics. The successful candidate will have prior experience in molecular biology, protein engineering, and flow cytometry. Experience with display technologies (yeast, phage or mammalian) is preferred. Come join us! Our integrated antibody discovery and engineering platform provides unprecedented speed from antigen to purified, full-length human IgGs with exquisite specificity and biophysical behavior. We offer fundamental advantages by delivering diverse panels of antibodies that meet the most demanding standards for affinity, epitope specificity, species cross-reactivity, and developability. We enable our partners to rapidly expand their biologics pipelines through a broad spectrum of technology access arrangements. As a profitable privately-held biotech company, we take a long-term view on value creation and make substantial investments in technology development, research, and our people. We offer individually tailored compensation packages comprised of a competitive salary, meaningful equity, a 2:1 401(k) match, and comprehensive health care benefits. Located in New Hampshire’s beautiful Upper Connecticut River Valley, we are minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and the Dartmouth Hitchcock Medical Center. We are fortunate to be situated in an area that is renowned for its premier skiing, hiking, kayaking, and biking.

Requirements

B.S., or equivalent practical experience, with training in molecular biology, chemical engineering, or biochemistry
At least 2 years of lab experience in an academic or industry setting
Knowledge of molecular biology, protein engineering, structural biology, and/or flow cytometry
Meticulous approach to benchwork and data analysis

Nice To Haves

B.S. or M.S. with training in molecular biology, chemical engineering, biochemistry or a related field
4+ years of relevant industry or research experience
Strong foundation in molecular biology, protein engineering and flow cytometry
Experience with protein display technologies (yeast, bacterial and/or ribosomal) desired
Experience with protein sequence analysis and next-generation sequencing workflows desired
Experience with protein structural analysis or computational design methods desired
Demonstrated ability to evaluate, interpret, and present scientific data clearly
Self-directed with a proven track record of executing independently at the bench and driving projects to completion
Highly organized with the ability to manage multiple projects simultaneously
Adaptable and productive in a fast-paced environment
Communicates effectively and openly with colleagues and supervisors
Resourceful with outstanding problem-solving skills
Quantitatively proficient, including demonstrated competency in Microsoft Excel

Responsibilities

Support Adimab’s antibody discovery, maturation, and production platform through:
Designing and executing protein engineering experiments
Constructing yeast display libraries and performing FACS selections
Performing protein and DNA sequence and basic 3D structural analysis
Collecting, organizing, and interpreting antibody characterization data
Collaborating effectively with colleagues and external partners