Program Manager II- Site Activations

Iterative Health•Cambridge, NY

10h•$115,000 - $165,000

About The Position

Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. The Iterative Health Site Network is a premier network of 70+ clinical research sites across US and Europe accelerating the path to market for gastrointestinal (GI) and hepatology novel therapies. Our focus is on driving the success and growth of our partner sites by empowering them with tech-enabled services. By combining deep expertise in clinical trials with cutting-edge AI, we empower research teams and study sponsors to expand and expedite access to novel therapeutics for patients in need. About the Role We are seeking a Program Manager II, Site Activations to own and scale the site activation process across the organization. This role is responsible for driving on-time site activations within SLAs, proactively identifying and resolving blockers, and improving activation workflows to increase speed, predictability, and efficiency. This role requires a strong operator who can manage complex details and dependencies day-to-day, while also stepping back to identify systemic issues, design better processes, and drive continuous improvement. The Program Manager II operates with a high degree of autonomy and is trusted to run site activations with limited oversight.

Requirements

5–8 years of experience in program management, operations, or project management
Proven track record of managing complex, cross-functional programs with tight timelines
Strong execution skills with exceptional attention to detail
Ability to zoom out and think systemically about process design and efficiency
Proven track record of delivering process improvements at scale
Excellent written and verbal communication skills, particularly around escalation and stakeholder management
High degree of ownership, judgment, and comfort operating independently
Experience in clinical research, site operations, healthcare, or life sciences

Nice To Haves

Experience scaling or maturing operational programs in growing organizations
Familiarity with activation tools, workflow systems, or project management platforms

Responsibilities

Program Ownership & Execution Own the end-to-end site activations, managing timelines, dependencies, and risks across multiple concurrent sites and trials
Be able to help teams prioritize tasks across multiple activations
Ensure activation milestones are met within defined SLAs, escalating risks and delays proactively
Maintain clear activation plans, status tracking, and documentation
Serve as the primary point of accountability for activation delivery
Cross-Functional Coordination & Escalation Coordinate across cross-functional partners (e.g., clinical operations, regulatory, legal, professional services)
Identify, document, and escalate blockers with clear context, impact, and recommended solutions
Drive alignment and follow-through across stakeholders with differing priorities
Facilitate discussions and decisions to keep activations moving forward
Process Improvement & Scaling Identify bottlenecks and inefficiencies in the activation lifecycle using data and operational insights
Lead initiatives to streamline workflows, reduce activation cycle times, and improve SLA adherence
Standardize processes, templates, and operating rhythms to support scale, with an eye towards automation
Partner with leadership to evolve the activation model as volume and complexity grow
Metrics & Reporting Own activation-related metrics, including time-to-activation, SLA performance, and root causes of delays
Define and maintain reporting and dashboards that provide clear visibility to stakeholders
Use data to inform prioritization, process improvements, and resourcing decisions
Leadership & Influence Act as a subject matter expert for site activation processes
Influence without authority, driving outcomes through clarity, structure, and accountability