Research Associate / Senior Research Associate, Strain Engineering

Switch BioworksSan Carlos, CA
10h$90,000 - $135,000Onsite

About The Position

As a Research Associate / Senior Research Associate (grade will be commensurate with qualifications and experience), you will be a core driver of our strain engineering R&D efforts, turning genetic designs into sustainable solutions. You will join a collaborative, fast-moving team where your role extends beyond the bench; we are looking for a scientist who is eager to bring on new methods, optimize workflows, and contribute to high-level experimental strategy. You will directly drive and execute design-build-test-learn cycles for novel microbial strains, conducting high-throughput screens and rigorous data analysis to accelerate Switch’s mission toward biofertilizer production.

Requirements

  • Must be authorized to work full-time in the U.S. and able to work on-site daily in the California Bay Area.
  • MS/BS in molecular biology, biochemistry, microbiology, synthetic biology, or a related field with 5+ years of industry experience or equivalent. Title would be commensurate with qualifications.
  • Proven experience in microbial molecular genetics and the engineering of bacterial chromosomes (≥2 years).
  • State-of-the-art DNA design and construction HTP workflows (3+ years)
  • Proficient in aseptic techniques and culturing diverse microorganisms.
  • Strong attention to detail, problem-solving ability, and critical thinking.
  • Excellent oral and written communication skills.
  • Comfortable standing for extended periods and handling delicate lab equipment.
  • Eager to both share and receive constructive feedback.
  • Able to start no later than May 2026.

Nice To Haves

  • Experience in engineering non-model or Gram-positive bacteria.
  • Experience the use of CRISPR in prokaryotic hosts.
  • Experience in extracting DNA from soil samples for NGS library preparation and downstream data analysis.

Responsibilities

  • Engineer microbial strains to enhance plant growth-promoting traits.
  • Design and build genetic circuits in non-model bacteria using modern assembly and recombination methods (e.g., Golden Gate, Gibson Assembly, CRISPR, etc).
  • Develop and leverage high-throughput workflows to optimize strain engineering.
  • Execute and analyze physiological, protein, and biochemical assays to evaluate strains.
  • Maintain detailed records and rigorously analyze data to ensure reproducibility.
  • Contribute actively to experimental design and daily planning.
  • Present scientific plans and results clearly to the team.
  • Work effectively both independently and within cross-functional teams.
  • Champion a culture of rigorous lab safety.
  • Leverage current literature to help shape the broader scientific strategy.
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