Research Scientist II

New York State Psychiatry InstituteNew York, NY
1dOnsite

About The Position

The Research Foundation for Mental Hygiene is seeking a qualified candidate to fill a full-time Research Scientist II. The Research Scientist must have experience in Stem Cells Research and iPSC differentiation into neurons, CRISPR technology, stem cell-based disease modeling, validation and assessment of cellular phenotypes, integrate splicing-aware transcriptomics, trans atomics, and proteomics in patient-derived neurons, data visualization, reporting, scientific writing, and must have an interest in neurodegenerative diseases. The researcher's daily tasks involve performing experiments like cell culturing and genetic modification, analyzing and documenting data, maintaining detailed lab records, troubleshooting experimental issues, and reading scientific literature to stay current with advances. They will prepare research for publication, present findings at conferences, and manage lab equipment to contribute to understanding stem cell behavior and developing new regenerative therapies. Experimental and Lab Work Cell Culture: Regularly feeding and maintaining stem cell lines, ensuring their sterility, growth, and viability. Experimentation: Designing and conducting experiments to study how stem cells grow, differentiate, and respond to various conditions or genetic modifications. Genetic Modification: Applying techniques like CRISPR gene editing to modify stem cells for specific research purposes. Microscopy and Imaging: Using advanced microscopes and imaging techniques to visualize cells and analyze cellular processes. Molecular Biology: Employing techniques such as PCR and DNA sequencing to study DNA, RNA, and protein components of cells. Troubleshooting: Identifying and resolving issues that arise with experimental protocols and procedures.

Requirements

  • Bachelor's degree and (3) years of professional research experience in an appropriate field or master's degree in an appropriate field may substitute for one year of experience, and Ph.D. in an appropriate field may substitute for an additional year of experience.
  • (5-6 )years of post-graduate experience in the stem cell field
  • Experience in Stem Cells Research and iPSC differentiation into neurons
  • CRISPR technology
  • Stem cell-based disease modeling
  • Validation and assessment of cellular phenotypes
  • Integrate splicing-aware transcriptomics, trans atomics, and proteomics in patient-derived neurons
  • Data visualization
  • Reporting
  • Scientific writing

Nice To Haves

  • An interest in neurodegenerative diseases

Responsibilities

  • Cell culturing and genetic modification
  • Analyzing and documenting data
  • Maintaining detailed lab records
  • Troubleshooting experimental issues
  • Reading scientific literature to stay current with advances
  • Prepare research for publication
  • Present findings at conferences
  • Manage lab equipment to contribute to understanding stem cell behavior and developing new regenerative therapies
  • Regularly feeding and maintaining stem cell lines, ensuring their sterility, growth, and viability.
  • Designing and conducting experiments to study how stem cells grow, differentiate, and respond to various conditions or genetic modifications.
  • Applying techniques like CRISPR gene editing to modify stem cells for specific research purposes.
  • Using advanced microscopes and imaging techniques to visualize cells and analyze cellular processes.
  • Employing techniques such as PCR and DNA sequencing to study DNA, RNA, and protein components of cells.
  • Identifying and resolving issues that arise with experimental protocols and procedures.

Benefits

  • Excellent Benefits Package.
  • Affirmative Action/Equal Opportunity Employer - Disabled/Veteran, 41 CFR 60-741.5(a) and 41 CFR 60-300.5(a) compliant.
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