Scientist 3 - Translational Medicine (Ophthalmology)

Roche • South San Francisco, CA

4d • Onsite

About The Position

Scientist 3 - Translational Medicine (Ophthalmology) Who We Are Genentech's Translational Medicine OMNI (TM OMNI) Department supports the entire R&D portfolio of novel therapies in Ophthalmology, Metabolism, Neuroscience, Immunology, and Infectious Diseases (OMNI). We develop and implement biomarker strategies to study disease pathways, confirm a therapeutic's mechanism of action, and improve clinical trial efficiency and success. Additionally, we lead reverse translation efforts, leveraging clinical data to support target discovery. The Position We are seeking a talented and highly motivated Scientist 3/4 to join Genentech’s Translational Medicine (TM) team on-site at our South San Francisco campus. The candidate will collaborate with scientists across R&D to provide biomarker support for ophthalmology programs across different stages of drug development while also generating insights for the next generation of ophthalmology drug targets. The role will cover: 1) Analysis and interpretation of large-scale -omics datasets from clinical and preclinical studies to enable biomarker discovery and reverse translation; 2) Assay development to support biomarker assessment in clinical and preclinical studies.

Requirements

• A PhD in Biological Sciences with a strong record of high-impact publications with both bioinformatics and wet lab experience.
• Excellent teamwork, communication, time management, organization skills, and ability to work independently.
• Excellent oral and written presentation skills, creative problem-solving abilities, and a passion for drug discovery and development.

Nice To Haves

• Industry experience preferred.

Responsibilities

• Analyze large scale -omics datasets (proteomics, lipidomics, transcriptomics) generated from clinical and preclinical sample testing.
• Discover candidate targets based on interpretation of -omics data and a deep understanding of disease biology.
• Develop, qualify, and validate custom immunoassays (e.g., ELISA, Simoa, NULISA) against biomarkers of interest to support pipeline programs (goes beyond running commercial assay kits).
• Clearly and concisely communicate findings internally and externally through written reports, publications, and presentations.
• Coordinate interdepartmental and external collaborations.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree