Scientist, Analytical Development

Landmark Bio • Watertown, MA

1d

About The Position

We are hiring a Scientist with excellent technical aptitude to join our company. This is an outstanding opportunity for a candidate to execute Analytical Sciences strategy in a cross-functional collaborative environment supporting development and cGMP manufacturing of cell and gene therapies. Scope of Responsibilities Application of analytical and biophysical characterization techniques such as flow and nanoflow cytometry, ELISA, qPCR/ddPCR and protein analytics. Analytical assay development for cell and gene therapy. Assay qualification and tech transfer activities to QC. Performance of general laboratory tasks, including maintenance and troubleshooting of equipment Maintain accurate and reliable records including database management, lab notebooks, and all other pertinent documentation. Writing and/or contributing to protocols, test methods and reports. Comply with all environmental health and safety standards. This is a hands-on lab-based position requiring a flexible schedule based on experimental work

Requirements

• Ph. D. in chemical engineering, biology, biotechnology, or related discipline or Master’s degree with 5+ years or Bachelor’s degree with 8+ years of relevant experience.
• Strong team worker who is also independently motivated, detail oriented and possesses good problem-solving capabilities.
• Demonstrated ability to work both independently as well as part of interdisciplinary team.
• Excellent organizational skills
• Strong verbal and written skills; able to handle confidential information and material appropriately

Nice To Haves

• PhD with a minimum of two, MS with a minimum of eight years of appropriate work experience in cell and gene therapy or related discipline are preferred.
• Demonstrate experience using protein and genome-based techniques (e.g. nanoparticle characterization, gel electrophoresis, western blotting, capillary electrophoresis, flow/nanoflow cytometry, ELISA and qualitative/quantitative PCR (qPCR, dPCR, ddPCR)).
• Experience/knowledge of extracellular vesicles to physically, chemically and biologically characterize.
• Experience/knowledge to support, in-process characterization, method transfer and release testing of drug substance and drug products.
• Experience in multiple aspects of aseptic mammalian cell culture, cell enumeration and phenotypic characterization.

Responsibilities

• Application of analytical and biophysical characterization techniques such as flow and nanoflow cytometry, ELISA, qPCR/ddPCR and protein analytics.
• Analytical assay development for cell and gene therapy.
• Assay qualification and tech transfer activities to QC.
• Performance of general laboratory tasks, including maintenance and troubleshooting of equipment
• Maintain accurate and reliable records including database management, lab notebooks, and all other pertinent documentation.
• Writing and/or contributing to protocols, test methods and reports.
• Comply with all environmental health and safety standards.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree