Scientist, Chemistry
About The Position
Octant is seeking a driven and curious Scientist to serve as the chemistry subject matter expert on our OpenADMET team. In this role, you will apply your physical organic chemistry expertise to guide data collection and interpretation. You will play a strategic role in determining how and when we execute synthesis, driving key collaborations, and advancing our platform technologies. At a high level, you’ll play a hands-on role in leveraging Octant’s Navigator platform to synthesize and analyze novel small molecules that modulate disease-relevant cellular mechanisms. Specifically, you will support the OpenADMET initiative at Octant by building libraries targeting the “avoidome” to generate high quality data to fuel machine learning model development. You will also expand our platform chemistry capabilities by pioneering novel synthetic and analytical methods. Finally, you will serve as a liaison between platform and drug program teams, leveraging your expertise to further Octant’s drug discovery efforts.
Requirements
- PhD in Organic Chemistry, Chemical Biology, or related field with 0-3 years experience post PhD as a post doctoral candidate or industry scientist
- Expertise with multi step organic synthesis, purification and analysis (HPLC, LC/MS, NMR)
- Familiarity with the application of LC-MS methods for proteomics or high throughput screening
- Experience with laboratory automation platforms and high-throughput screening methods
- Excellent problem-solving and communication skills
Nice To Haves
- Experience coding for data analysis, visualization or lab automation (e.g., Python)
- Familiarity with high-throughput experimentation and direct-to-biology high throughput chemistry approaches
Responsibilities
- Serve as the chemistry subject matter expert on our OpenADMET team
- Apply your physical organic chemistry expertise to guide data collection and interpretation
- Play a strategic role in determining how and when we execute synthesis, driving key collaborations, and advancing our platform technologies.
- Play a hands-on role in leveraging Octant’s Navigator platform to synthesize and analyze novel small molecules that modulate disease-relevant cellular mechanisms.
- Support the OpenADMET initiative at Octant by building libraries targeting the “avoidome” to generate high quality data to fuel machine learning model development.
- Expand our platform chemistry capabilities by pioneering novel synthetic and analytical methods.
- Serve as a liaison between platform and drug program teams, leveraging your expertise to further Octant’s drug discovery efforts.
Benefits
- health benefits (medical, dental, vision)
- equity
- 401(k) matching
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
