Scientist I

WuXi AppTec•San Diego, CA

About The Position

HD Biosciences, Inc. (San Diego), a WuXi AppTec Company, is expanding its Plate-based Pharmacology team. We’re seeking a highly skilled and motivated Scientist to develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats. Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques. Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred. Responsibilities • Design, implement, and perform projects for functional assay development. • Independently develop and performing assays to evaluate biologic drug candidates, such as ELISA, western blot, kinase assays, etc.• Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats• Effectively communicate with internal team colleagues and external clients to promote world-class servicesEssential Job Functions:• Provides operational support for (Specific Dept.) activities including (Ex. media/buffer preparation, cleaning activities, and equipment/materials staging/ Aseptic Technique)• Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required• Works under close supervision from supervisor or senior personnel• Normally receives minimal instructions on routine work and detailed instructions on new assignments• Performs support functions (e.g. Runner function) on the Plate-based Pharmacology team • Contributes to the overall operations and to the achievement of departmental goals• Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.• Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices• May be required to assist in other departments • Other duties as assigned

Requirements

PhD degree (Biochemistry, Biotechnology or Molecular Biology), work experience preferred or Master’s degree (Biochemistry, Biotechnology or Molecular biology) with 2 years of related work experience or Bachelor’s degree (Biochemistry, Biotechnology or Molecular biology) with 4 years of related work experience
Proven hands-on experience with cell based assays and biochemical assays
Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques
Demonstrated strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology
Excellent written, oral and interpersonal communication skills
Scientific creativity, critical thinking and fast learning capabilities
Ability to work in a team environment and independently as required
Must be able to read, write and understand English
Proficient in Microsoft (Excel, Word, Outlook)
Must be able to work in an office environment with minimal noise conditions.
Must be able to work in Lab setting with exposure to Animals, biohazards, chemicals
Must not have animal allergies to applicable species in this facility
Must be able to wear appropriate PPE
Must be able to work in environment with variable noise levels
Ability to stand/sit/walk for long periods of time
Ability to Lift 10 lbs. routinely
Ability to crouch, bend, twist, and reach
Ability to push/pull 10 lbs. routinely
Clarity of Vision
Ability to identify and distinguish colors
Must be able to perform activities with repetitive motions
Ability to climb stairs
Ability to work in variable temperatures high to freezing
Inside/outside working conditions

Nice To Haves

Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred
Industry experience in Pharma/Biotech and/or drug R&D process is preferred

Responsibilities

Design, implement, and perform projects for functional assay development.
Independently develop and performing assays to evaluate biologic drug candidates, such as ELISA, western blot, kinase assays, etc.
Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats
Effectively communicate with internal team colleagues and external clients to promote world-class services
Provides operational support for (Specific Dept.) activities including (Ex. media/buffer preparation, cleaning activities, and equipment/materials staging/ Aseptic Technique)
Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required
Works under close supervision from supervisor or senior personnel
Normally receives minimal instructions on routine work and detailed instructions on new assignments
Performs support functions (e.g. Runner function) on the Plate-based Pharmacology team
Contributes to the overall operations and to the achievement of departmental goals
Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.
Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices
May be required to assist in other departments
Other duties as assigned