Scientist, Multispecifics Engineering - Discovery Biotherapeutics

AbbVie • Worcester, MA

1d

About The Position

Discovery Biotherapeutics at AbbVie is seeking a highly motivated research scientist to join our dynamic team supporting biologics drug discovery and multispecifics engineering. This position will contribute to projects through the discovery and engineering of biopharmaceutical products. The ideal candidate will bring strong experience in antibody and multispecifics design and production, molecular biology, and have knowledge of antibody fragments and mimetics. Additional desirable skills include expertise in antibody engineering, protein purification, and familiarity with sequence analysis tools. The candidate should be able to analyze, document, and report data, possess excellent communication skills, and feel comfortable presenting in group settings.

Requirements

• BS or MS in biology or related discipline with typically 5-8+ years (BS), or 2-5+ years (MS) of pharmaceutical and/or relevant experience
• Protein, biologics, fragments, and multi-specifics purification
• Mammalian cell culture for protein expression
• In vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
• Strong molecular biology skills (e.g. molecular cloning)
• Familiarity with sequence analysis tools (Vector NTI, Geneious, Genedata)
• Excellent oral and written communication skills
• Excellent organizational skills and the ability to execute on multiple projects simultaneously
• Team player capable of operating in a fast-paced, multidisciplinary environment, adapting to rapid changes in project priorities and timelines
• Proficiency with software programs including MS Excel, PowerPoint, and Word

Nice To Haves

• Experience with antibody engineering, design, and optimization
• Experience overseeing CROs for DNA and protein production
• Hands-on experience with SEC, HIC, IEX purification of complex biologics utilizing AKTA platforms
• Experience utilizing automation (e.g. Hamilton, AssayMap, Kingfisher) equipment in biologics discovery processes
• Proficiency in mass spectrometry interpretation for complex biologics
• Proficiency with software programs: Geneious, Genedata, Unicorn

Benefits

• paid time off (vacation, holidays, sick)
• medical/dental/vision insurance
• 401(k)
• short-term incentive programs

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level