Senior Associate Scientist

Bristol Myers Squibb • Seattle, WA

3d • Onsite

About The Position

The Senior Associate Scientist will join the Automation Process Development team and support the development and qualification of scale down models for automated cell manufacturing suits (AMS) with focus on transduction process development. The role involves hands-on execution of experiments, including lentiviral vector titration and the development of bioreactor/automated processing system scale down models. The successful candidates will collaborate closely with cross-functional teams to advance process understanding and support technology transfer activities.

Requirements

• MS or BS degree in Biomedical Engineering, Cell Biology, Immunology, or related field with relevant industry experience preferably in cell therapy, gene therapy, or bioprocess development (MS with 1+ years, or BS with 3+ years
• Hands-on experience with cell culture, viral vector handling, and bioreactor and/or automated processing systems.
• Strong analytical and problem-solving skills.
• Excellent written and verbal communication skills, including drafting study protocols and reports.
• Excellent organizational, documentation, and communication abilities.
• Ability to work independently and collaboratively in a fast-paced, team-oriented environment.

Nice To Haves

• Experience in developing, qualifying, and utilizing scale-down models for process development, preferred.
• Knowledge of GxP regulations and regulatory requirements for cell therapy manufacturing is a plus.
• Proven experience designing DOE and high-throughput process screening studies, preferred.
• Familiarity with process characterization, QbD (Quality by Design) principles, and regulatory submissions (IND, BLA) is a plus.

Responsibilities

• Develop, optimize, and qualify scale down models for bioreactor and automated cell processing systems, simulating large-scale manufacturing conditions.
• Perform lentiviral vector titration assays to determine viral particle concentration and support process development activities.
• Prepare cell culture media, reagents, and samples for experimental procedures.
• Operate and maintain laboratory equipment used in cell therapy process development.
• Collect, analyze, and interpret experimental data, document results in electronic laboratory notebooks.
• Ensure all work is performed in compliance with safety guidelines, standard operating procedures, and regulatory requirements.
• Collaborate with team members to design experiments, share findings, and support project goals.
• Prepare technical reports, presentations, and documentation for internal and external stakeholders.
• Participate in technology transfer activities and support scale-up of processes as needed.
• Maintain accurate and detailed laboratory records in accordance with BMS policies and regulatory requirements.
• Stay current with advances in cell therapy manufacturing and automation technologies, applying relevant innovations to scale-down model development.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
• All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level