Senior Automation Engineer

Wave Life Sciences • Lexington, MA

11d • $98,000 - $132,000 • Onsite

About The Position

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline includes clinical programs in Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency and Huntington’s disease, as well as a clinical program in obesity and a preclinical program in NASH/MASH. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease. Description: Reporting to the Director of Engineering, the Senior Automation Engineer will own automation-related tasks, projects, and support for GMP manufacturing systems. Core responsibilities will include automation and I&C-related maintenance and troubleshooting, owning / supporting automation-related projects on GMP equipment, including installation, startup, commissioning, testing and qualification of automated systems at Wave’s Lexington Manufacturing site. Additionally, the Senior Automation Engineer will contribute to the design and implementation of new control systems during facility expansions and equipment upgrades. This person must be capable of working independently and collaboratively across functional areas to enable the manufacturing of Wave’s investigational products. Experience: Degree in Engineering discipline or equivalent 3-5 years of demonstrated experience in industrial automation, instrumentation, and controls applied in support of cGMP manufacturing operations, equipment, and / or facilities Experience managing / supporting engineering and capital projects

Requirements

• Degree in Engineering discipline or equivalent
• 3-5 years of demonstrated experience in industrial automation, instrumentation, and controls applied in support of cGMP manufacturing operations, equipment, and / or facilities
• Experience managing / supporting engineering and capital projects
• Experience with automation systems such as Allen Bradley or Siemens PLC platforms, Delta V DCS platform, Schneider Electric or Johnson Controls BMS platforms, iFix, Factory Talk, ignition SCADA systems, data systems (PI, IP21, Crystal Reports etc.) and data integration solutions (OPC, Kepware, Matrikon, LabX, Web API, etc.)
• SQL databases experience (e.g. backups, restoration, relocation)
• Knowledgeable in VMware/Vshpere environment
• Experience in Programmable Logic Controller or Distributive Control System programming, and Data Historian and Report Configuration
• Proficient understanding of instrumentation, and its configuration, Industrial Control networking such as Ethernet IP, Profibus, or AS-I networks
• Demonstrated experience of Windows OS, Networking & System Security Fundamentals
• Experience with ISA-S88, ISA-S95, and ASTM 2500 principles
• Familiarity with 21 CFR Part 11 and data integrity
• Ability to climb ladders and work in tight spaces with equipment (bending, squatting, twisting)
• Able to lift objects of 25-50 pounds, push/pull objects, apply firm grasp and/or reach above shoulder height, and gown in/out of cleanroom areas
• Must be able to use personal cell phone for emergency team, as necessary

Responsibilities

• Maintain and improve automation systems, instrumentation, and controls that are used on GMP equipment and to monitor manufacturing operations
• Lead automation and I&C-related troubleshooting activities in partnership with internal subject matter experts and equipment vendors
• Develop processes to improve GMP equipment automation and I&C reliability
• Develop and maintain Engineering Specifications (URS, FRS, DDS, HDS, SDS), drawings, standard operating procedures (SOPs), and preventative maintenance plans
• Manage projects focused on the modification of existing cGMP control systems and infrastructure (on equipment and stand-alone systems)
• Provide automation support to aid the design and implementation of new GMP equipment
• Author, review, and execute commissioning / validation protocols and engineering test plans
• Own quality events related to equipment automation and systems
• Train internal teams on automated systems and automation best practices
• Work primarily onsite at Wave’s Lexington facility

Benefits

• This position is eligible for a discretionary annual bonus and discretionary stock-based long-term incentives.
• In addition to compensation, Wave offers a comprehensive and competitive range of benefits designed to support our employees’ and their families physical and financial health and overall well-being. These include, but are not limited to, company-sponsored medical, dental, vision, life, long and short-term disability insurances, generous paid time off (including a week-long company shutdown in the Summer and the Winter), 401K participation with matching contributions, and Employee Stock Purchase Program.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 251-500 employees