Senior Director – Assistant Controller

Caris Life Sciences•Irving, TX

About The Position

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins. Position Summary The Senior Director – Assistant Controller is responsible for supporting the Controller in ensuring the integrity of the Company’s financial information through compliance with U.S. GAAP, SEC reporting requirements, and Company policies and procedures. This role oversees all core accounting operations, and ensures timely and accurate financial reporting, a disciplined month-end close process, and a strong internal control environment. The Senior Director – Assistant Controller leads key accounting functions including general ledger, operating expenses, accruals, prepaids, cash, payroll accounting, fixed assets, leases, cost accounting, consolidations, intercompany, and technical accounting implementation. This leader will drive process improvements, scalability, and automation to support a growing public company environment. This role partners closely with Finance, Internal Audit, IT, Legal, HR, and other cross-functional teams to support financial transparency, operational excellence, and regulatory compliance.

Requirements

Bachelor’s degree in Accounting or related field
CPA required
12+ years of progressive accounting experience, including a combination of public accounting (Big 4 preferred) and public company experience
5+ years of leadership experience managing managers and cross-functional teams
Strong experience in U.S. GAAP and SOX compliance within a public company environment
Demonstrated experience leading and improving the month-end close process
Strong ERP systems experience; involvement in system implementations or upgrades preferred
Advanced proficiency in Microsoft Office Suite, particularly Excel

Nice To Haves

Experience in life sciences, healthcare, diagnostics, or other regulated industries
Experience scaling accounting operations in a newly-public, high-growth environment
Strong technical accounting background.

Responsibilities

Lead and manage the monthly, quarterly, and annual close processes for all accounting areas
Ensure timely and accurate preparation and review of journal entries, account reconciliations, and supporting schedules
Oversee consolidations, intercompany eliminations, and general ledger integrity
Maintain a disciplined close calendar and continuously improve close efficiency
Partner with SEC Reporting to ensure completeness and accuracy of financial information supporting external filings
Support technical accounting implementation and new accounting standards adoption
Oversee accounting for operating expenses, accruals, prepaid assets, fixed assets, leases, cost accounting, cash, and payroll
Review complex accounting transactions and significant estimates
Ensure proper balance sheet management and reconciliation discipline across all assigned areas
Oversee payroll accounting, including related compliance and audit support
Implement and enhance internal controls over financial reporting (first year SOX compliance)
Partner with Internal Audit and external auditors to support quarterly reviews and annual audits
Ensure appropriate documentation of policies, procedures, and accounting positions
Proactively identify control gaps and implement remediation plans
Lead accounting process optimization and automation initiatives
Partner with IT and Finance on ERP enhancements and system implementations
Collaborate with other departments such as legal, compliance, HR, etc. in process improvement and standardizing procedures
Develop scalable processes to support company growth and operational complexity
Establish KPIs and metrics to monitor accounting performance and efficiency
Lead, develop, attract and hire accounting leaders and team members across assigned functions
Establish clear accountability, performance expectations, and development plans
Foster a culture of ownership, continuous improvement, and collaboration