Senior Manager, High-Throughput Screening Operations- San Diego, CA

dsm-firmenich • San Diego, CA

2d • $132,000 - $188,000

About The Position

Join a dynamic and innovative research program at the forefront of chemosensory science. As Senior Manager of High-Throughput Screening (HTS) Operations, you will lead a multi-disciplinary team exploring chemosensory receptor-driven perception and its applications in taste and health. Your leadership will directly impact scientific discovery and the advancement of health solutions through cutting-edge small molecule research.

Requirements

• Ph.D. in Molecular or Cell Biology, Neuroscience, Pharmacology, or a related field
• At least 8 years of industry experience in high-throughput screening or related settings
• Demonstrated success in leading scientific teams and managing HTS laboratory operations
• Proven record of HTS-aided small molecule discovery leading to candidate selection
• Extensive knowledge of HTS procedures, assays, compound management, and automation technologies
• Strong organizational and communication skills with a collaborative, multidisciplinary approach
• Expertise in GPCR or ion channel pharmacology and structure-function analysis, with advanced data analysis capabilities

Nice To Haves

• Experience supporting computer-aided discovery within HTS operations preferred
• Development of data analysis pipelines using R or Python strongly preferred

Responsibilities

• Manage and mentor a group of four or more scientists and associates within high-throughput screening operations
• Oversee day-to-day activities in HTS and compound reformatting laboratories
• Foster a problem-solving mindset and promote innovative approaches to research challenges
• Ensure efficient scheduling and supervision of all workflow processes
• Maintain and optimize the use of screening, liquid handling, and automation instruments
• Supervise the transfer of assays from Biology to the HTS group, ensuring robustness and reproducibility
• Manage and reformat collections of compounds and natural samples for daily operations
• Monitor assay performance, identify and resolve technical issues, and ensure data integrity
• Review and analyze screening data to drive discovery program success
• Partner with Data Science and Chemistry teams to enable AI-driven operations and data analysis
• Contribute to the design and implementation of new HTS assays by staying current with emerging technologies
• Prepare and submit scientific manuscripts, patent applications, and internal reports to top peer-reviewed journals

Benefits

• Opportunities to contribute to projects with significant health and social benefits
• A highly creative, imaginative team culture that encourages curiosity and open-mindedness
• Support for your professional growth and development through career advancement opportunities
• Dynamic application of Machine Learning and advanced modeling in biology and chemistry
• A collaborative, results-oriented organizational culture focused on scientific excellence
• A workplace that prioritizes your safety and well-being, both physically and mentally
• Competitive pay, outstanding benefits, and a rewarding compensation program

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree