Senior Software Engineer, Backend and Cloud - Product

Prima Mente•San Francisco, CA

About The Position

Prima Mente is a frontier biology AI lab. We generate our own data, build general-purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco, and Dubai. Role Focus – Senior Software Engineer, Backend & Cloud You will design, build, and scale SaaS systems that bring biological foundation models to real users. Role split approximately 70% backend, 25% cloud, 5% frontend. You will build products that support: Working with large biological datasets with heavy I/O and structured metadata Experiment lineage, artifact tracking, and model version history Tenant-aware access controls and role-scoped permissions Reproducible workflows that bridge research code and production services You will work on turning complex model workflows into products that are usable, reliable, and observable in production.

Requirements

Strong backend development in Python, Go, or similar
Experience designing and operating REST or gRPC APIs in production
RDMS schema design and performance tuning (PostgreSQL preferred)
Production experience in AWS or GCP
Experience provisioning and deploying cloud resources
Docker-based development
Experience deploying services to Kubernetes
Practical experience building and maintaining React applications
Familiarity with infrastructure as code
Experience using Terraform

Responsibilities

Design and implement REST or gRPC APIs that power datasets, experiments, and user workflows
Define service boundaries and evolve them as the system grows
Design, migrate, and optimize schemas in an RDMS (PostgreSQL preferred)
Implement authentication and tenant-level authorization controls
Improve performance, query efficiency, and data integrity
Add structured logging and metrics to support fast debugging
Deploy and operate services in AWS or GCP
Provision and configure compute, storage, and service-level networking
Configure IAM roles with least-privilege access
Containerize services with Docker
Deploy and debug applications in Kubernetes
Use infrastructure as code to manage environments (Terraform preferred)
Improve monitoring and operational reliability
Contribute to React / Next.js features when needed
Integrate backend APIs cleanly with frontend surfaces
Debug issues across UI, API, database, and cloud
Maintain clear API contracts and system boundaries