Sr Bioinformatics Scientist

Illumina • San Diego, CA

2d • Remote

About The Position

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Why Us We are a multi-disciplinary and multinational team focused in using next-generation sequencing technology to transform human health and save patient’s lives. Our team works at the interface of research and clinical practice developing and improving innovative algorithms to call variants and biomarkers that fill gaps in clinical practice, focusing primarily on oncology. We collaborate deeply with internal and external teams, to augment DRAGEN, Illumina’s software platform to analyze high-throughput sequencing data, and remove barriers for its use in clinical settings. Why You We know the importance of your role and offer you a collaborative and supportive environment in which you are actively encouraged to develop your skills and knowledge. Illumina's mission is to improve human health by unlocking the power of the genome - if that inspires you, let's talk. If you are excited as we are about using genomics to transform the practice of medicine, have a proven track record of algorithm development, data analysis, and strong coding ability, this is the role for you. You will be part of a culture fueled by innovation, collaboration, and openness. To be successful as a Sr Bioinformatics Scientist, you will need a background in bioinformatics with a particular focus on algorithm development, biomarkers and oncology. Previous experience with at least two of statistics, common bioinformatics methods, next generation sequencing analysis, and oncology will be key to your success. This role may be performed remotely within the US but the position requires accommodation to meeting times to overlap with Pacific time zone hours. The Role The Sr Bioinformatics Scientist will drive the development of secondary analysis algorithms for variant and biomarker detection to support treatment decisions based on the cancer’s molecular profile. This role will also involve designing R&D studies, to demonstrate the clinical utility of NGS in oncology treatment and prototyping software implementations.

Requirements

• Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience.
• PhD in bioinformatics, computation biology, statistics, math or related field or equivalent work experience preferred
• Fluency in at least two of statistics, common bioinformatics methods NGS analysis, and oncology.
• Experience developing bioinformatics NGS algorithms beyond leveraging already existing tools.
• Fluency in programming languages such as Python.
• Good communication skills to contribute to cross functional project teams and work with stakeholders.

Nice To Haves

• Experience with C++ is desired

Responsibilities

• Assess and improve existing secondary analysis algorithms for variant and biomarker detection
• Prototype novel secondary analysis algorithms
• In collaboration with external and internal experimental teams, design and analyze experiments to support existing or new Illumina oncology assays.
• Provide technical guidance to internal and external collaborators.
• Participate in cross functional assay and algorithm R&D teams with minimal oversight.
• Effectively communicate plans and results across functions

Benefits

• all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package
• We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.
• We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission.
• Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics.
• We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race.
• We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree