Principal Scientist, Kidney Disease Research Expert - In Vitro, CVRI

Bayer•Cambridge, MA

About The Position

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice. Principal Scientist, Kidney Disease Research Expert - In Vitro, CVRI Bayer has an opening for a Principal Scientist to join our Cardiovascular-Renal In Vitro Research group based at the Bayer Innovation Campus at the heart of Kendall Square in Cambridge, MA, to further strengthen our experience in the kidney disease space globally and help build up a team of researchers at this site. We are looking for an expert scientist with deep knowledge of Kidney Disease Biology and demonstrated experience with the discovery and development of therapeutics. This is an excellent opportunity for a highly motivated candidate interested in driving and growing our therapeutics pipeline in a vibrant and collaborative atmosphere.

Requirements

A Ph.D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field.
A strong background in kidney disease biology is essential, and further expertise in cardiovascular or metabolic space would be highly advantageous.
Demonstrated track record in the drug discovery process in a pharmaceutical or biotech setting would be highly advantageous.
A deep knowledge and hands-on experience in designing and establishing translatable functional cellular disease models (2D or 3D) to aid target identification and therapeutic evaluation.
Deep expertise in the application of state-of-the-art in vitro methods across the early drug discovery process (including molecular biology, biochemistry, and cellular analytical techniques).
Experience in the design and execution of early-stage research program(s) to identify and validate novel targets
Excellent verbal and written communication and interpersonal skills to work across functions and within external collaborations, and a demonstrated ability to organize and communicate complex data sets in a clear and concise manner to cross-functional audiences
Ability to adapt to and effectively manage changes in a fast paced and dynamic environment
A passion for science and sense of urgency to find new medicines to benefit patients

Nice To Haves

8+ years of relevant post-PhD experience including 4+ years in industry is preferred, with a proven record of successful team leadership and interaction with collaborators

Responsibilities

In preclinical programs, act as disease biology lead ensuring excellence in kidney biology sounding as well as alignment and timely delivery of pharmacology related deliveries to efficiently advance programs towards milestones and go/no go decisions, including concise and regular presentation of program results to senior stakeholders.
Support and contribute to the drug development strategy of CVRI, with particular focus on kidney diseases and the intersection of the cardiovascular, renal, metabolic space.
Design and supervise the execution of functional cellular disease models to support target identification, therapeutic candidate characterization, and mechanism of action evaluations.
Provide scientific leadership and seek innovative solutions (internally and externally) in the application of in vitro methods to support our early discovery pipeline.
Contribute key documentation and presentations for projects moving through internal review stage gates and regulatory submissions.
Support the management and coaching of research associates and junior scientists in a matrix organization.
Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators.
Assess external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration or technological innovation.
Maintain and extend a network with external partners from academia, contract research organizations and medical experts.
Foster creativity and motivation between scientists.