Senior Research Associate I, Services (P-4964)

10x Genomics•Pleasanton, CA

1d•Onsite

About The Position

We're in search of an exceptional Senior Research Associate I to join our Translational and Research Services Team. You'll be an integral part of a highly collaborative new team at 10x, focused on demonstrating the value of 10x products and providing top notch services to external customers. As a Senior Research Associate, you will be responsible for performing the analysis of biological tissue samples. This will involve supporting all aspects of the process, from sample intake, sample QC and assay performance, and initial analysis and QC of the data, ensuring the highest quality results are achieved throughout the entire process. The successful candidate in this position will work closely with expert scientists in cellular genetics and proteomics and will have the opportunity to participate in the development of high profile cutting edge tools in analytical biology. You bring a strong background in the biological sciences and have acquired significant experience in conducting single cell genomic assays, ideally using 10x Genomics product lines. You possess excellent communication skills, are detail oriented and can effectively collaborate with interdisciplinary teams, integrating their feedback into your experimental design. Your high motivation, proactiveness, and adaptability allow you to navigate changing priorities and methods with ease. Thriving in fast-paced environments, you excel at managing multiple priorities, communicating clearly, and consistently delivering results.

Requirements

B.S. or equivalent, in Microbiology, Molecular Biology, Biochemistry, or a related field with 3+ years lab experience
Experience working in similar positions in an industry service provider/core facility
Experience with molecular biology techniques and related equipment, including NGS library preparation workflows, flow cytometry, microscopy, high-throughput single cell genomics (e.g. QuantumScale, 10x Genomics Chromium assays)
A proven track-record of using, optimizing and troubleshooting molecular biology protocols
Strong customer service orientation, with a commitment to project success
Demonstrated flexibility in collaborating with cross-functional internal groups
Strong organizational skills and ability to plan and structure your work
Excellent interpersonal skills, including written and oral communication
Ability to work in a fast-paced and quickly changing environment
Capacity for repetitive tasks

Nice To Haves

Experience with a variety of tissue types for single cell analysis (e.g., nuclei, PBMCs, complex neurological tissues)
Basic coding skills (Nextflow ideal)
Experience with image analysis using relevant analytical tools (e.g. CellProfiler, ImageJ)
Flow cytometry experience (e.g., BD FACS Melody, Sony Cell Analyzer, Agilent NovoCyte)
Knowledge and troubleshooting experience with liquid handling or automated systems (e.g. Integra, Biomek, Hamilton)
Familiarity with LIMS

Responsibilities

Perform single cell assays with a wide range of tissue inputs
Perform flow cytometry
Perform a variety of NGS library preparation workflows
Troubleshoot assays in collaboration with the assay team
Optimize protocols for specific tissue samples
Improve workflows and provide feedback to development and marketing teams
Deliver processed sequencing data to, and work closely with, computational biologists, project managers, and other scientific investigators
Generate and maintain meticulous laboratory records, SOPs, and batch records
Ensure work is conducted with appropriate quality controls
Manage sample receipt, tracking and storage
Forecast reagent and material needs for services
Operate and assist with the maintenance of lab equipment dedicated to services
Maintain a well organized lab and identify and implement efficiency improvements