Senior Research Associate

Intellia • Cambridge, MA

5d • $90,000 - $110,000 • Onsite

About The Position

Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together. Intellia is seeking a highly skilled and motivated Senior Research Associate to join our RNA Technologies team. This is a position with a primary focus on building and executing upon processes to synthesize mRNA for our lead Crispr/Cas9 gene editing programs. The ideal applicant will be able to work on mRNA synthesis and characterize mRNA quality. Experience with oligonucleotide enzymatic and/or chemical synthesis, basic nucleic acid biochemistry and molecular biology is preferred.

Requirements

• Experience in small-scale and mid- scale in vitro transcription workflows.
• Excellent verbal and written communication skills.
• Excellent organizational skills and attention to detail.
• Excellent time management skills with a proven ability to meet deadlines.
• Strong analytical and problem-solving skills.
• Ability to function well in a high-paced and at times stressful environment.
• Ability to multitask and handle a diverse array of challenges within a dynamic team environment.
• Bachelor’s Degree in Biochemistry, Chemistry, Biology or related field or Master's Degree
• Bachelor’s Degree in Biochemistry, Chemistry, Biology or related field with at least 2-3 years ( co-op, internship, or research assistant ) experience or Master's Degree with 0-1 years of industry experience
• Optimal fine motor skills
• Prolonged periods of sitting
• Lifting/carrying lab supplies up to 20-25lbs

Nice To Haves

• Experience with oligonucleotide enzymatic and/or chemical synthesis, basic nucleic acid biochemistry and molecular biology is preferred.

Responsibilities

• Synthesize RNA from DNA template sources leveraging established enzymatic in vitro transcription processes to deliver high quality transcripts for downstream applications at small and medium scales
• Leverage existing workflows to purify and characterize RNAs by established methods depending on RNA scale and purpose.
• Execute routine mRNA production batches to meet company’s deadlines with manager guidance
• Collaborate with colleagues to further develop enzymatic processes and analytical methods to characterize and improve key quality attributes of novel RNAs.
• Provide high quality data to drive decision making in the team.
• Operate and maintain multiple laboratory instruments.
• Assist in maintaining general laboratory functionality.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level