Senior Scientist, Translational Research

Bristol Myers Squibb

2d • Onsite

About The Position

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area. Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

We are seeking an experienced individual with oncology research expertise to join the Translational Research team within the Oncology Thematic Research Center at Bristol Myers Squibb in Cambridge, MA. The qualified candidate is a highly motivated, engaged, and creative scientist that can thrive in a highly matrixed organization to advance programs from candidate optimization through IND enabling activities and ultimately to Proof-of-Concept clinical trials. This individual will play a pivotal role in shaping and driving translational strategies for oncology assets, enabling the development of transformative cancer therapies for patients.

Requirements

• Bachelor’s Degree 7+ years of academic and / or industry experience
• Or Master’s Degree 5+ years of academic and / or industry experience
• Or Ph.D. or equivalent advanced degree in the Life Sciences 2+ of academic and / or industry experience

Nice To Haves

• PhD with 2+ years of relevant industry experience in the Oncology drug development process is required.
• Oncology translational biomarker roles and with solid tumor and immune oncology experience is preferred.
• Strong scientific acumen and mechanistic understanding of disease biology, with experience contributing to oncology and immuno-oncology drug development.
• Hands-on experience designing, executing, and analysing translational biomarker assays and data across multiple technologies (e.g., genomics, immunohistochemistry, flow cytometry, immunoassays) and sample types in clinical studies.
• Familiarity with the drug development process and experience collaborating with clinical teams; able to communicate results and contribute to discussions in cross-functional settings.
• Demonstrated ability to work effectively with internal stakeholders and external partners (e.g., CROs, specialty labs).
• Excellent communication, organizational, and teamwork skills, with a proactive and collaborative mindset.
• Eagerness to learn, grow, and take on increasing responsibility in a fast-paced environment.

Responsibilities

• Design and develop biomarker, pharmacodynamic, and target engagement assays to understand drug mechanism of action and response.
• Perform laboratory-based experiments and data analysis to support clinical oncology studies, using various in vitro oncology and cancer immunology models and assays.
• Interact with project teams and contract laboratories for the design, execution, and oversight of molecular, cellular, and/or in vivo studies.
• Collaborate with cross-functional teams and external partners (CROs, specialty labs) to generate high-quality biomarker data for clinical studies.
• Contribute to translational plans, sample collection strategies, and documentation for early-phase trials.
• Present experimental results and share scientific insights with project teams and stakeholders.
• Proactively provides insight into novel ways to incorporate biomarkers into clinical designs to enable early understanding of emerging drug profiles, as well as input around tumor types and potential impact of biomarkers on internal decision making.
• Provides oversight to progress validated biomarkers into development of diagnostic assays, as needed
• Participates in strategic review and input to presentations, publications and internal/ external communications along with accountable program leadership and in governance forums
• Develops solutions and courses of action for senior staff, including identification of risks and risk mitigations
• Shares expertise, experience, lessons learned and knowledge with translational and other relevant scientific experts and colleagues across the organization

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree