Scientist - Protein Biochemistry

GSK • Cambridge, MA

1d • Onsite

About The Position

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK’s long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life. Find out more: Our approach to R&D Position Summary As a Scientist, you will be expected to be able to use your knowledge of biochemistry and biophysics to independently design and execute experiments with guidance from the lab head and project teams. You must be self-motivated to deliver vaccine program objectives on time and be able to identify and mitigate any potential delays.

Requirements

• PhD with 0+ years of post-doc and/or job-related experience, MS with 3+ years of experience, or BS with 6+ years of experience.
• Three or more years of experience on a wide variety of molecules such as recombinant soluble proteins, membrane proteins, mAbs, and viral like particles.
• Three or more years of hands-on experience on protein purification utilizing affinity purification, anion exchange, and size exclusion chromatography.
• Three or more years of hands-on experience on biophysical techniques including Octet/SPR, DLS, nano-DSF, CPS-Disc, HPLC, UPLC, and protein stability assays.

Nice To Haves

• Prior experience with one or more of the following: Working with PyMOL to observe and analyze structures.
• Experience on Negative scan electron microscopy.
• Collaborating with large project teams in a matrix environment.
• Excellent communication skills to effectively convey complex scientific data.
• Basic skills in statistical analysis.

Responsibilities

• Apply biochemistry and biophysics expertise to the design and development of GSK vaccine projects.
• Implementation of new technologies to help drive vaccine development.
• Perform high throughput screening and purification of recombinant soluble proteins, membrane proteins, mAbs, and viral like particles.
• Develop and conduct assays to evaluate the biophysical properties of the vaccine candidates.
• Possesses strong scientific leadership to enable collaboration with key scientific internal and external stakeholders.
• Publish in peer reviewed journals.

Benefits

• In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role.
• Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree